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Three Core Differences: Temperature Stability Range SLU-PP-332: Stable from -40C to 180C 5-amino-1MQ: Optimal range 10C to 120C Dissolution Speed SLU-PP-332: 85% dissolution in 25 minutes 5-amino-1MQ: 95% dissolution in 15 minutes pH Tolerance SLU-PP-332: Stable between pH 3.0-11.0 5-amino-1MQ: Optimal between pH 4.5-9.2 External lab tests have shown that SLU-PP-332 works better in harsh situations than other materials
Discontinuations attributed to adverse events occurred in 12.2% of those receiving 9 mg, 18.2% of those receiving 12 mg, and 4.0% of placebo recipients, with higher BMI at baseline associated with increased likelihood of discontinuation
Gel-forming antioxidant eye drop efficacy in an intravitreal paraquat (PQ) model of RP in rats Retinal degeneration was induced in 4-week-old Brown Norway rats following intravitreal injection (3 L) of 2 mM PQ
